产品货号：
Z11864
中文名称：
BNIP3抗体
英文名称：
Anti-BNIP3 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-BNIP3 Antibody |
| 指标别名 | BNIP3;NIP3 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB |
| 基因名称 | BNIP3 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthetic peptide corresponding to a sequence of human BNIP3 (KEFLFKHPKRTATLSMRNTSVMKK). |
| 实际分子量 | 21KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | The Bcl-2 nineteen kilodalton interacting protein 3 (BNIP3 or NIP3),is a hypoxia-inducible proapoptotic member of the Bcl-2 family that induces cell death by associating with the mitochondria.BNIP3,expressed in skeletal muscle and in the brain at low levels,is primarily localized to the nucleus of glial cells of the normal human brain,as well as in the malignant glioma cell line U251.BNIP3 expression in the cytoplasm increases and localizes with the mitochondria,contributing to induction of cell death.Cellular protein BNIP3 interacts with E1B-19K,BCL-2,BCL-xL,and EBV-BHRF1.BNIP3 contains Bcl-2 homology 3 (BH3) domain and COOH-terminal transmembrane (TM) domain.The BH3 domain of BNIP3 mediates Bcl-2/Bcl-X(L) heterodimerization and confers pro-apoptotic activity;whereas the TM domain is critical for homodimerization,pro-apoptotic function,and mitochondrial targeting. |
| Uniprot ID | Q12983 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 推荐稀释比 | Western blot(WB) 1:500～2000 |
相关搜索：BNIP3抗体，BNIP3多抗，Anti-BNIP3 Antibody